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On 17 June, the Evaluation Committee for the VNUHCM-level research project entitled ‘Research and fabrication of gold metallic nanostructured plasmonic substrates for surface-enhanced Raman spectroscopy applications,’ chaired by MSc Nguyễn Duy Khánh, alongside Associate Professor Lê Vũ Tuấn Hùng and Dr Lê Văn Ngọc.

The project focused on the research and fabrication of SERS (Surface-Enhanced Raman Scattering – surface-enhanced Raman spectroscopy) sensor substrates based on gold nanostructures. These substrates are designed for the detection of Auramine O, a hazardous organic dye subject to strict regulation in food safety.

During the investigation, the research group fabricated three distinct gold nanostructure morphologies: gold nanospheres (GNS), gold nanorods (GNR), and gold nanourchins (GNU). The team subsequently evaluated how material morphology influences the efficiency of Raman signal enhancement.

A key highlight of the research is the systematic assessment of the relationship between gold nanostructure morphology and SERS performance under identical measurement conditions. The findings demonstrate that the SERS signal increases in the order of GNS3 < GNR120 < GNU25. Specifically, the gold nanourchin structure (GNU25) achieved the highest enhancement efficiency due to the high density of sharp spikes on the surface, which facilitates the formation of numerous electromagnetic ‘hot spots’—localised sites capable of strongly amplifying the Raman signal.

The experimental results indicate that the GNU25-structured SERS substrate achieved the lowest limit of detection for Auramine O at 0.01 mg/L. The fabricated SERS substrates also demonstrated excellent uniformity, reproducibility, and stability after six months of storage. These outcomes help guide the development of high-performance plasmonic nanomaterials for rapid, sensitive, and non-destructive Raman sensing systems, benefiting fields such as food safety, environmental monitoring, and analytical chemistry.

Within the framework of this project, the research group published one international paper in a journal ranked Q2 by SCImago, whilst contributing to the training of one doctoral candidate and two undergraduate students.

The Evaluation Committee commended the project for appropriate research content, feasible methodologies, reliable results, and practical application value. Having fulfilled all the established objectives, the project was unanimously approved and highly commended by the Committee.